RainSure BCR-ABL (P210) Digital PCR Kit: One-Step, Ultra-Sensitive Detection for CML Monitoring

Precision Oncology Starts with Accurate BCR-ABL Detection

The BCR-ABL (P210) fusion gene is a critical biomarker for diagnosing and managing chronic myeloid leukemia (CML). Accurate and sensitive quantification of this gene is essential for monitoring disease progression, detecting minimal residual disease (MRD), and evaluating response to tyrosine kinase inhibitor (TKI) therapy.

The RainSure BCR-ABL (P210) Digital PCR Kit offers an industry-leading solution for ultra-sensitive, one-step detection—delivering results you can trust.

RainSure’s One-Tube Ultra Sensitive BCR-ABL Detection Kit

RainSure’s proprietary one-tube, digital PCR technology enables high-precision detection of BCR-ABL p210 transcripts with MR 5.0 sensitivity—allowing labs to detect even the lowest levels of residual disease.

Key Highlights:

· BCR-ABL p210 one-step detection digital PCR kit

· Multiplex design detects BCR-ABL and ABL in one reaction

· Absolute quantification without standard curves

· Compatible with major digital PCR platforms

· Validated for clinical research and patient monitoring

Applications in TKI Treatment and MRD Monitoring

Monitoring the BCR-ABL1 ratio in the blood of CML patients is essential to evaluate the effectiveness of TKI treatment such as imatinib, dasatinib, or nilotinib.

RainSure’s kit supports:

· Quantitative BCR-ABL monitoring for TKI treatment response

· Detection of MR 4.0–5.0 levels for early intervention

· Tracking remission or relapse risk during long-term follow-up

· Supporting treatment-free remission (TFR) studies

How It Works: Multiplex Digital PCR Made Simple

This advanced multiplex assay is designed to simultaneously detect BCR-ABL p210 and the internal control ABL gene in one reaction tube. This not only increases efficiency but also enhances reproducibility and minimizes contamination risk.

Workflow Benefits:

· One-step setup in a single tube

· Multiplex detection for internal normalization

· Quick turnaround with minimal hands-on time

· Digital PCR ensures high precision and low false negatives

Technical Specifications

Trusted by Leading Oncology Labs and Researchers

RainSure’s BCR-ABL p210 detection kit is trusted by:

· Clinical research labs

· Hospital molecular diagnostics units

· Pharmaceutical trial centers

· Academic hematology departments

Whether you're tracking treatment outcomes or designing a TKI clinical trial, RainSure ensures high-sensitivity molecular monitoring you can depend on.

Why MR 5.0 Sensitivity Matters

Achieving MR 5.0 (Molecular Response 5.0) means detecting 1 leukemic cell in 100,000 normal cells. This level of sensitivity is critical for:

· Determining if patients qualify for treatment-free remission

· Identifying relapse before clinical symptoms appear

· Enhancing patient-specific treatment planning

Learn More or Request a Sample

To explore how the RainSure BCR-ABL (P210) Digital PCR Kit can enhance your lab’s leukemia monitoring capabilities, visit www.rainsureglobal.com or contact your regional distributor.

Final Takeaway

For accurate, efficient, and ultra-sensitive BCR-ABL p210 detection, the RainSure one-tube ultra sensitive BCR-ABL detection kit sets the benchmark. Its digital PCR precision, MR 5.0 sensitivity, and multiplex design make it an indispensable tool for modern CML diagnostics and treatment monitoring.