RainSure Scientific Human BCR-ABL (P210) Fusion Gene Detection Kit: The Gold Standard in Digital PCR for CML

What Is the BCR-ABL (P210) Fusion Gene?

The BCR-ABL P210 fusion gene is a hallmark of chronic myeloid leukemia (CML). It results from a translocation between chromosomes 9 and 22, creating the Philadelphia chromosome, which produces an abnormal tyrosine kinase protein that drives uncontrolled cell division.

Detecting this fusion gene with high sensitivity is critical for:

· Diagnosing CML

· Monitoring minimal residual disease (MRD)

· Assessing treatment response

Why Choose Digital PCR for BCR-ABL Detection?

Unlike conventional PCR or qPCR, digital PCR (dPCR) offers:

· Absolute quantification (no need for standard curves)

· Higher sensitivity and precision

· Better reproducibility

· Enhanced detection of low-level mutations and MRD

This makes digital PCR the preferred method for laboratories that demand ultra-sensitive detection and quantification.

About the RainSure Human BCR-ABL (P210) Fusion Gene Detection Kit

The RainSure Scientific BCR-ABL (P210) Fusion Gene Detection Kit leverages cutting-edge digital PCR technology to deliver unparalleled performance for the detection of BCR-ABL transcripts.

Key Features:

· ✅ Highly Specific Probes: Designed for the P210 transcript variant

· ✅ Digital PCR Platform Compatibility: Optimized for standard droplet digital PCR systems

· ✅ Ultra-Sensitive Detection: Ideal for detecting low-copy events in MRD

· ✅ Quantitative Accuracy: Enables absolute copy number determination

· ✅ Fast Turnaround: Streamlined workflow for rapid results

Applications in Clinical and Research Settings

This kit is essential for:

· Clinical diagnostics: Initial CML diagnosis or confirmation

· Longitudinal monitoring: Track treatment response and remission

· MRD detection: Identify relapse at the earliest molecular sign

· Pharmaceutical trials: Quantitative biomarker in drug efficacy studies

What’s Included in the Kit?

· Digital PCR reagents (primers, probes)

· Positive and negative controls

· Reaction buffer optimized for droplet formation

· Protocol guide for reproducibility across labs

Who Uses the RainSure BCR-ABL Kit?

This kit is trusted by:

· Clinical laboratories

· Academic research institutions

· Biopharma companies

· Oncology-focused hospitals and diagnostic centers

Compatible Platforms

RainSure’s kit works seamlessly with most commercial digital PCR systems, including:

· Bio-Rad QX200™

· RainSure RS32 all-in-one digital PCR

· RainSure DropDx digital PCR

Why It Matters for CML Patient Management

· Early detection = Early intervention

· Precise quantification = Tailored therapy decisions

· Long-term monitoring = Better outcomes

This kit supports evidence-based treatment plans, helping clinicians and researchers stay ahead in the fight against CML.

Final Thoughts

Whether you're running a diagnostic lab or conducting leukemia research, the RainSure BCR-ABL (P210) Digital PCR Kit offers the accuracy, sensitivity, and trustworthiness you need. It's a critical tool for modern molecular oncology.

Learn More

For more details or to request a quote, visit RainSure Scientific’s official website or contact their technical sales team.

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