Rainsure Digital PCR: First 40-Plex Sepsis Detection for Whole Blood with ARG Monitoring

Rainsure Digital PCR: The First 40-Plex Sepsis Detection Solution for Whole Blood

Sepsis is a life-threatening medical emergency caused by the body’s response to infection. Early and accurate identification of pathogens is critical to saving lives. That’s why Rainsure Digital PCR has developed the world’s first digital PCR-based sepsis detection solution capable of processing whole blood samples, detecting 85% of common sepsis-causing pathogens, and providing 40-plex analysis in a single microfluidic cartridge.

This breakthrough enables ultra-rapid diagnosis, real-time treatment monitoring, and antibiotic resistance gene (ARG) detection—revolutionizing the way clinicians diagnose and manage sepsis.

Key Features of Rainsure’s Digital PCR Sepsis Panel

Whole Blood Compatibility

Unlike traditional molecular tests that require blood culture, Rainsure’s platform directly processes whole blood, significantly reducing time to results.

40-Plex Detection in One Cartridge

The Rainsure cartridge allows simultaneous analysis of up to 40 targets, including bacteria, fungi, and ARGs—ideal for comprehensive infection profiling in a single test.

Covers 85% of Common Sepsis Pathogens

The panel includes a broad spectrum of gram-positive, gram-negative bacteria, and fungi, accounting for 85% of clinically relevant sepsis cases worldwide.

Early Detection to Prevent Sepsis Escalation

By bypassing the need for culturing, Rainsure’s system enables early identification of pathogens—helping physicians initiate targeted therapy within hours of symptom onset.

ARG Detection for Precision Treatment

Simultaneously detect antibiotic resistance genes to guide appropriate antimicrobial therapy, reduce trial-and-error, and support antibiotic stewardship.

Patient Monitoring and Outcome Improvement

Use Rainsure Digital PCR to track pathogen load over time, assess treatment response, and prevent complications through ongoing monitoring.

Clinical Applications of Rainsure Digital PCR for Sepsis

Emergency and Critical Care

· Rapid diagnosis of bloodstream infections in ICU

· Guide immediate therapeutic decisions

· Monitor septic shock progression and recovery

Infectious Disease Labs

· Replace or complement blood culture workflows

· Reduce false negatives due to prior antibiotic use

· Improve diagnostic yield in complex cases

Antimicrobial Stewardship Programs (ASPs)

· Detect ARGs early to avoid broad-spectrum antibiotic overuse

· Track resistance trends at a population level

· Support hospital infection control policies

Why Rainsure dPCR for Sepsis?

Frequently Asked Questions

How does Rainsure improve sepsis diagnosis speed?

By eliminating the need for culturing and using digital PCR, Rainsure delivers highly sensitive results in under 2 hours, directly from whole blood.

What types of pathogens can Rainsure detect?

Gram-positive and gram-negative bacteria, fungi, and antibiotic resistance genes, covering 85% of global sepsis pathogens.

Can the test guide antibiotic treatment?

Yes. The panel includes ARGs to detect resistance mechanisms, helping clinicians tailor therapy precisely.

Is the test suitable for routine hospital use?

Absolutely. Rainsure’s microfluidic cartridge format and automated workflow make it ideal for clinical labs and emergency settings.

Conclusion

Rainsure Digital PCR offers a transformative approach to sepsis diagnostics: 40-plex testing, direct whole blood compatibility, early detection, and ARG monitoring—all in a rapid, cartridge-based format. By covering the majority of sepsis-causing pathogens and delivering actionable results in just hours, it empowers healthcare providers to make timely, life-saving decisions.

Accelerate sepsis diagnosis and improve outcomes with Rainsure Digital PCR. Learn more or request a demo today.