This kit is used to detect ALK (Anaplastic Lymphoma Kinase) G1269A mutation in tissue DNA and cfDNA of plasma samples.
ALK was first discovered in a subtype of anaplastic large cell lymphoma (ALCL), hence the name anaplastic lymphoma kinase (ALK). Subsequently, before the discovery of ALK gene rearrangements in non-small cell lung cancer, multiple types of ALK gene rearrangements were found in diffuse large B-cell lymphoma and inflammatory myofibroblastic tumor (IMT), respectively. ALK is a potent oncogenic driver gene.
(includes primer probes only)
Human ALK Gene G1269A Mutation Detection Kit (Fluorescent Probe Method)